Description

1-(3-Hydroxy-5-Trifluoromethyl-Phenyl)-Ethanone is a high-purity, functionalized aromatic ketone featuring both a hydroxyl and a trifluoromethyl group on the phenyl ring. This unique molecular structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block for synthesizing more complex organic molecules. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring fluorinated compounds for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a crucial precursor in the manufacture of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl group can improve efficacy and environmental profile.
• Liquid Crystal & OLED Material Research: Used in the synthesis of fluorinated organic compounds for electronic applications, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Functional Polymer Monomer: Acts as a building block for creating specialty polymers with specific optical, thermal, or surface properties.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new organic reactions, catalysis, and material science due to its reactive ketone and phenolic functionalities.
• Dye & Pigment Intermediate: Utilized in the synthesis of complex fluorinated dyes and pigments for high-performance applications.

Basic Information

Product Name	1-(3-Hydroxy-5-Trifluoromethyl-Phenyl)-Ethanone
CAS No.	1261826-34-9
Molecular Formula	C9H7F3O2
Molecular Weight	204.15 g/mol
Synonyms	3'-Hydroxy-5'-(trifluoromethyl)acetophenone; 1-[3-Hydroxy-5-(trifluoromethyl)phenyl]ethanone; 3-Acetyl-5-(trifluoromethyl)phenol; 3-Hydroxy-5-trifluoromethylacetophenone; 5-Trifluoromethyl-3-hydroxyacetophenone; 3-Hydroxy-α,α,α-trifluoro-m-acetophenone; m-Hydroxy-α,α,α-trifluoroacetophenone (5-isomer)
EINECS	Contact for details

Quality Control

Our production of 1-(3-Hydroxy-5-Trifluoromethyl-Phenyl)-Ethanone adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and structural identity. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system is designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.