Description

2-Bromo-3-Methoxybenzonitrile is a versatile and high-purity aromatic nitrile building block, essential for advanced organic synthesis. Its molecular structure, featuring bromine and methoxy substituents, makes it a critical intermediate for constructing complex molecules with precise electronic and steric properties. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in drug discovery, material science, and the synthesis of liquid crystals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzonitrile core.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the bromine atom serves as a handle for further functionalization.
• Material Science Research: Employed as a monomer or building block for creating specialized polymers, ligands, and organic electronic materials.
• Liquid Crystal Development: Serves as a core component in the synthesis of advanced liquid crystal compounds for display technologies.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Buchwald-Hartwig amination, enabling rapid diversification.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems.

Basic Information

Product Name	2-Bromo-3-Methoxybenzonitrile
CAS No.	1261816-95-8
Molecular Formula	C8H6BrNO
Molecular Weight	212.04 g/mol
Synonyms	3-Methoxy-2-bromobenzonitrile; 2-Bromo-3-methoxybenzonitrile; Benzonitrile, 2-bromo-3-methoxy-; 2-Bromo-m-anisonitrile
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Methoxybenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.