Description

2-Bromo-3-Chlorophenylacetonitrile is a versatile halogenated aromatic nitrile building block of significant interest in advanced organic synthesis. Its value lies in its bifunctional reactivity, where the nitrile and halogen substituents serve as key handles for constructing complex molecular architectures. This intermediate is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated phenyl core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials due to its rigid aromatic structure.
• Chemical Biology Probes: Useful for constructing molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical building block for fine chemical manufacturers offering bespoke synthesis services to global clients.

Basic Information

Product Name	2-Bromo-3-Chlorophenylacetonitrile
CAS No.	1261815-64-8
Molecular Formula	C8H5BrClN
Molecular Weight	230.49 g/mol
Synonyms	(2-Bromo-3-chlorophenyl)acetonitrile; 2-Bromo-3-chlorobenzyl cyanide; α-Cyano-2-bromo-3-chlorotoluene; Benzeneacetonitrile, 2-bromo-3-chloro-; 2-Bromo-3-chloro-α-tolunitrile; 1261815-64-8; (2-Bromo-3-chlorophenyl)ethanenitrile
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Chlorophenylacetonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, GC, and NMR, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.