Description

3-Amino-2-Iodobenzonitrile is a versatile halogenated aromatic amine building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both an amino group and an iodine atom on the benzonitrile core, makes it a critical intermediate for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science: Serves as a building block for organic electronic materials, ligands for catalysts, and specialty polymers.
• Medicinal Chemistry & Drug Discovery: Employed in structure-activity relationship (SAR) studies and library synthesis for hit-to-lead optimization.
• Cross-Coupling Reactions: The iodine atom makes it a valuable substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig couplings.
• Chemical Research: Used in academic and industrial R&D for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	3-Amino-2-Iodobenzonitrile
CAS No.	1261810-77-8
Molecular Formula	C7H5IN2
Molecular Weight	244.03 g/mol
Synonyms	2-Iodo-3-aminobenzonitrile; 3-Amino-2-iodobenzonitrile; Benzonitrile, 3-amino-2-iodo-; 2-Cyano-6-iodoaniline; 6-Iodoanthranilonitrile
EINECS	Contact for details

Quality Control

Our 3-Amino-2-Iodobenzonitrile is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We are committed to meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.