Description

4-Chloro-2-(Trifluoromethoxy)Benzamide, 97% is a high-purity fluorinated aromatic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the chloro and trifluoromethoxy substituents impart unique physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce these functional groups into complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Material Science Research: Acts as a monomer or precursor for developing advanced polymers, liquid crystals, or organic electronic materials with specific optical or electronic properties.
• Chemical Biology & Proteomics: Employed as a scaffold or labeling reagent in the design of chemical probes for studying enzyme function and protein interactions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	4-Chloro-2-(Trifluoromethoxy)Benzamide, 97%
CAS No.	1261791-05-2
Molecular Formula	C8H5ClF3NO2
Molecular Weight	239.58 g/mol
Synonyms	4-Chloro-2-(trifluoromethoxy)benzamide; 2-Trifluoromethoxy-4-chlorobenzamide; 4-Chloro-α,α,α-trifluoro-o-anisamide; Benzamide, 4-chloro-2-(trifluoromethoxy)-; 1261791-05-2; 4-Chloro-2-trifluoromethoxybenzamide
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(Trifluoromethoxy)Benzamide is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure the specified purity of 97% (min.) and to control critical impurities. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, ensuring full traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed immediately after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	97.0% min.
Related Substances (HPLC)	Total impurities: 3.0% max.
Water Content (KF)	0.5% max.
Residue on Ignition	0.1% max.

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.