Description

5-Bromo-2-(Hydroxymethyl)Benzonitrile is a versatile aromatic nitrile derivative featuring both bromo and hydroxymethyl functional groups. This compound serves as a critical pharmaceutical intermediate and organic synthesis building block, enabling the construction of complex molecules for drug discovery and material science. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Used to create specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Monomer or functionalizing agent in the development of advanced polymers and liquid crystals.
• Chemical Biology Probes: Serves as a starting point for synthesizing molecular probes and tags for biological target identification.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of client-specific compounds under cGMP or research-grade conditions.

Basic Information

Product Name	5-Bromo-2-(Hydroxymethyl)Benzonitrile
CAS No.	1261775-63-6
Molecular Formula	C8H6BrNO
Molecular Weight	212.05 g/mol
Synonyms	2-(Hydroxymethyl)-5-bromobenzonitrile; 5-Bromo-2-(hydroxymethyl)benzonitrile; 5-Bromo-2-cyanobenzyl alcohol; (5-Bromo-2-cyanophenyl)methanol; Benzonitrile, 5-bromo-2-(hydroxymethyl)-; 1261775-63-6
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(Hydroxymethyl)Benzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications from research to cGMP-grade production, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.