Description

2-Nitro-6-(Trifluoromethoxy)Anisole is a specialized aromatic building block featuring both nitro and trifluoromethoxy functional groups, which are critical for modulating electronic and steric properties in advanced molecular architectures. This compound is valued for its role in the synthesis of complex agrochemicals and pharmaceuticals, where its unique substitution pattern enables the development of novel active ingredients. It is primarily sought by R&D chemists and process development scientists in the fine chemical, agrochemical, and pharmaceutical industries for creating new compounds with enhanced biological activity and physical properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Serves as a precursor for novel herbicides and insecticides, leveraging the bioactivity of the nitro and trifluoromethoxy motifs.
• Material Science Research: Used in the development of advanced organic materials, such as liquid crystals and organic semiconductors.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing specialized azo dyes and pigments with specific color fastness and stability properties.
• Cross-Coupling Reactions: An effective substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing complex biaryl systems.

Basic Information

Product Name	2-Nitro-6-(Trifluoromethoxy)Anisole
CAS No.	1261764-67-3
Molecular Formula	C8H6F3NO4
Molecular Weight	237.14 g/mol
Synonyms	1-Methoxy-2-nitro-3-(trifluoromethoxy)benzene; 2-Nitro-1-(trifluoromethoxy)-3-methoxybenzene; Benzene, 1-methoxy-2-nitro-3-(trifluoromethoxy)-; 3-Methoxy-2-nitro-1-(trifluoromethoxy)benzene; 2-Nitro-6-(trifluoromethoxy)methoxybenzene; 6-(Trifluoromethoxy)-2-nitroanisole
EINECS	Contact for details

Quality Control

Every batch of 2-Nitro-6-(Trifluoromethoxy)Anisole is produced under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.