Description

2-Amino-4-(Trifluoromethoxy)Benzamide is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoromethoxy-substituted benzamide structure. This compound is of significant commercial interest for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted bioactivity. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new drug candidates and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug molecules, especially for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, leveraging the stability imparted by the trifluoromethoxy group.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in catalytic systems and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of organic electronic materials and specialty polymers.
• Bioconjugation & Probe Synthesis: Useful for creating fluorescent probes or affinity labels for biochemical and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke chemical synthesis projects in fine chemical production.

Basic Information

Product Name	2-Amino-4-(Trifluoromethoxy)Benzamide
CAS No.	1261724-55-3
Molecular Formula	C8H7F3N2O2
Molecular Weight	220.15 g/mol
Synonyms	4-(Trifluoromethoxy)-2-aminobenzamide; 2-Amino-4-(trifluoromethoxy)benzamide; Benzamide, 2-amino-4-(trifluoromethoxy)-; 4-Trifluoromethoxyanthranilamide; 2-Amino-α-oxo-4-(trifluoromethoxy)benzenemethanamine; 4-(Trifluoromethoxy)anthranilamide; 2-Amino-4-(trifluoromethoxy)benzoic acid amide
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(Trifluoromethoxy)Benzamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. We provide a Certificate of Analysis (COA) with every shipment, detailing all specifications to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.