Description

3-Chloro-4-Iodobenzonitrile is a halogenated benzonitrile derivative, a versatile and high-value organic intermediate prized for its unique reactivity profile. Its molecular structure, featuring both chloro and iodo substituents on an aromatic nitrile core, makes it a critical building block for constructing complex molecules in advanced research and development. This compound is essential for pharmaceutical chemists, agrochemical researchers, and material scientists engaged in the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the halogenated aromatic system contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organocatalysis, enabling novel synthetic transformations.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers where the introduction of halogen atoms tunes electronic properties and molecular packing.
• Cross-Coupling Reactions: The iodine atom is an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira), allowing for precise structural diversification.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and tags used in bio-conjugation and imaging studies.

Basic Information

Product Name	3-Chloro-4-Iodobenzonitrile
CAS No.	1261686-46-7
Molecular Formula	C7H3ClIN
Molecular Weight	263.46 g/mol
Synonyms	4-Iodo-3-chlorobenzonitrile; 3-Chloro-4-iodobenzene carbonitrile; Benzonitrile, 3-chloro-4-iodo-; 3-Chloro-4-cyanoidobenzene; 3-Chloro-4-iodophenyl cyanide; 4-Cyano-2-chloro-1-iodobenzene; 2-Chloro-4-cyanoidobenzene
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Iodobenzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and consistent lot-to-lot performance. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.