Description

2-Methyl-5-(Trifluoromethoxy)Benzonitrile, 97% is a high-purity, fluorinated aromatic nitrile building block of significant interest in advanced chemical synthesis. This compound is valued for its unique trifluoromethoxy substituent, which imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the trifluoromethoxy group can improve biological activity and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display technologies and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with tailored thermal, chemical, or surface properties.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Sonogashira) and cyano-group transformations for constructing complex molecular architectures.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and material science applications.

Basic Information

Product Name	2-Methyl-5-(Trifluoromethoxy)Benzonitrile, 97%
CAS No.	1261679-13-3
Molecular Formula	C9H6F3NO
Molecular Weight	201.15 g/mol
Synonyms	5-(Trifluoromethoxy)-2-methylbenzonitrile; 2-Methyl-5-(trifluoromethoxy)benzonitrile; 2-Methyl-α,α,α-trifluoro-p-cresol nitrile; 2-Methyl-5-trifluoromethoxybenzonitrile; 5-(Trifluoromethoxy)-o-tolunitrile; Benzonitrile, 2-methyl-5-(trifluoromethoxy)-; α,α,α-Trifluoro-2-methyl-p-cresol nitrile
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-(Trifluoromethoxy)Benzonitrile, 97% is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the specified standard. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.