Description

Methyl 3-(2'-Fluoro-5'-Iodophenyl)Propionate CAS NO 1261650-03-6 is a high-purity fluorinated and iodinated aromatic ester building block. This compound is valued for its unique halogenated structure, which makes it a critical intermediate in advanced organic synthesis, particularly for constructing complex molecules with specific electronic and steric properties. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in drug discovery and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of fluorinated drug candidates targeting CNS disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and pesticides, where the fluorine and iodine atoms can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis, enabling challenging cross-coupling reactions.
• Material Science Research: Employed in the synthesis of advanced organic materials, such as liquid crystals or organic semiconductors, where halogenated aromatics tune electronic properties.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic & Industrial R&D: Utilized in exploratory chemistry for method development and creating compound libraries for high-throughput screening.

Basic Information

Product Name	Methyl 3-(2'-Fluoro-5'-Iodophenyl)Propionate
CAS No.	1261650-03-6
Molecular Formula	C10H10FIO2
Molecular Weight	308.09 g/mol
Synonyms	3-(2-Fluoro-5-iodophenyl)propionic acid methyl ester; Methyl 3-(2-fluoro-5-iodophenyl)propanoate; 2-Fluoro-5-iodo-β-methylcinnamate; Methyl (2-fluoro-5-iodohydrocinnamate); 1261650-03-6; 3-(2-Fluoro-5-iodo-phenyl)-propionic acid methyl ester; Propanoic acid, 3-(2-fluoro-5-iodophenyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-(2'-Fluoro-5'-Iodophenyl)Propionate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and compliance needs in advanced synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0% (Area %)
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Heavy Metals	<10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	<0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.