Description

1H-Pyrrolo[2,3-B]Pyridine-2-Carbonitrile is a high-purity nitrogen-containing heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile and critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key scaffold in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides with specific modes of action.
• Material Science: Acts as a precursor for organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology: Employed as a probe or tag in the design of molecules for studying biological pathways.
• Academic & Contract Research: Utilized in universities and CROs for methodological development and discovery chemistry projects.
• Custom Synthesis: A starting point for the contract manufacturing of proprietary compounds and advanced intermediates.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-2-Carbonitrile
CAS No.	1261627-31-9
Molecular Formula	C8H5N3
Molecular Weight	143.15 g/mol
Synonyms	7-Azaindole-2-carbonitrile; 1H-Pyrrolo[2,3-b]pyridine-2-carbonitrile; 2-Cyano-7-azaindole; 2-Cyano-1H-pyrrolo[2,3-b]pyridine; 7-Aza-2-cyanoindole; 2-CN-7-azaindole; Azaindole-2-carbonitrile derivative
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-2-Carbonitrile is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.