Description

Ethyl 2-(3-Fluoro-4-Iodophenyl)Acetate is a high-purity, fluorinated and iodinated aromatic ester building block of significant interest in advanced organic synthesis. This compound is valued for its unique halogenated structure, which provides versatile reactivity for constructing complex molecular architectures. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for use as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the fluorine and iodine substituents for enhanced biological activity and metabolic stability.
• Ligand & Catalyst Synthesis: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science: Employed in the research and development of advanced organic electronic materials and liquid crystals.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and tags for imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated intermediates.

Basic Information

Product Name	Ethyl 2-(3-Fluoro-4-Iodophenyl)Acetate
CAS No.	1261606-34-1
Molecular Formula	C10H10FIO2
Molecular Weight	308.09 g/mol
Synonyms	Ethyl (3-Fluoro-4-iodophenyl)acetate; 2-(3-Fluoro-4-iodophenyl)acetic Acid Ethyl Ester; Acetic acid, 2-(3-fluoro-4-iodophenyl)-, ethyl ester; Ethyl 3-Fluoro-4-iodobenzeneacetate; Ethyl α-(3-Fluoro-4-iodophenyl)acetate; 1261606-34-1; Ethyl (3-Fluoro-4-iodobenzyl)acetate (common misnomer)
EINECS	Contact for details

Quality Control

Our Ethyl 2-(3-Fluoro-4-Iodophenyl)Acetate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications. Our quality commitment supports applications in GMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.