Description

3-Bromo-2-Methoxyphenylacetonitrile is a versatile and high-purity organic building block of significant importance in advanced chemical synthesis. Its molecular structure, featuring both bromo and cyano functional groups adjacent to a methoxy-substituted aromatic ring, makes it a critical intermediate for constructing complex molecules. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and material science industries, where it is used to introduce key molecular fragments in target-oriented synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing substituted benzyl or phenethylamine cores.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and advanced polymers.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and tags for studying biological systems.
• Custom Synthesis and Contract Manufacturing: A valuable building block for fine chemical companies offering bespoke synthesis services.

Basic Information

Product Name	3-Bromo-2-Methoxyphenylacetonitrile
CAS No.	1261602-72-5
Molecular Formula	C9H8BrNO
Molecular Weight	226.07 g/mol
Synonyms	(3-Bromo-2-methoxyphenyl)acetonitrile; 2-(3-Bromo-2-methoxyphenyl)acetonitrile; 3-Bromo-2-methoxybenzyl cyanide; α-Cyano-3-bromo-2-methoxytoluene; Benzeneacetonitrile, 3-bromo-2-methoxy-; 1261602-72-5; (3-Bromo-2-methoxy-phenyl)-acetonitrile
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-2-Methoxyphenylacetonitrile is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. Our standard grade typically meets a purity specification of ≥97% (by HPLC), with detailed control of related substances. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing identity, assay, and impurity profiles. We support custom synthesis and can tailor specifications to meet specific project requirements, including compliance with ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.