Description

2-Chloro-3,4-Difluorophenylacetic Acid is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its core value lies in its versatile molecular structure, which serves as a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a difluorinated phenylacetic acid scaffold.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, where the chloro-difluoro substitution pattern can influence bioactivity and environmental stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for advanced functional materials, where fluorination is used to fine-tune electronic properties, thermal stability, and optical characteristics.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, esterifications, and amide bond formations to introduce a halogenated, fluorinated aromatic segment into target molecules.
• Chemical Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	2-Chloro-3,4-Difluorophenylacetic Acid
CAS No.	1261598-59-7
Molecular Formula	C8H5ClF2O2
Molecular Weight	206.57 g/mol
Synonyms	(2-Chloro-3,4-difluorophenyl)acetic Acid; 2-(2-Chloro-3,4-difluorophenyl)acetic Acid; 2-Chloro-3,4-difluorobenzeneacetic Acid; α-(2-Chloro-3,4-difluorophenyl)acetic Acid; 1261598-59-7; 2-Chloro-3,4-difluoro benzene acetic acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-3,4-Difluorophenylacetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.