Description

3,5-Difluoro-4-Methylanisole is a high-purity fluorinated anisole derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms and a methoxy group, which are essential for modulating the electronic properties, lipophilicity, and metabolic stability of target molecules. This compound is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Material Science Precursor: Employed in the synthesis of specialty monomers for fluorinated polymers and advanced liquid crystal materials.
• Organic Electronics: Acts as a building block for electron-transport materials and charge-modifying layers in OLED and OFET applications.
• Cross-Coupling Reactions: Serves as a versatile substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed coupling reactions to create complex biaryl structures.
• Chemical Research: Utilized in academic and industrial laboratories for method development and exploring new fluorination chemistry pathways.

Basic Information

Product Name	3,5-Difluoro-4-Methylanisole
CAS No.	1261478-94-7
Molecular Formula	C8H8F2O
Molecular Weight	158.15 g/mol
Synonyms	4-Methyl-3,5-difluoroanisole; 1,3-Difluoro-2-methoxy-5-methylbenzene; Benzene, 1,3-difluoro-2-methoxy-5-methyl-; 3,5-Difluoro-4-methyl-1-methoxybenzene; 2-Methoxy-1,3-difluoro-5-methylbenzene; 3,5-Difluoro-p-cresol methyl ether; 4-Methyl-3,5-difluorophenyl methyl ether
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-4-Methylanisole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for fine chemical intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.