Description

Telmisartan-13Cd3 is a stable isotope-labeled analog of the antihypertensive drug Telmisartan, specifically deuterated at three positions with carbon-13. This high-purity reference standard is essential for ensuring the accuracy and reliability of quantitative bioanalytical methods. It is primarily used by pharmaceutical R&D laboratories, contract research organizations (CROs), and regulatory testing facilities for applications in drug metabolism and pharmacokinetics (DMPK) studies.

Application

• Internal standard for the precise quantification of Telmisartan in biological matrices (e.g., plasma, serum, urine) using LC-MS/MS.
• Critical component in method development and validation for bioequivalence and bioavailability studies.
• Use in pharmacokinetic (PK) and pharmacodynamic (PD) research to track drug absorption, distribution, metabolism, and excretion (ADME).
• Calibration standard for ensuring regulatory compliance in GLP (Good Laboratory Practice) and GCP (Good Clinical Practice) environments.
• Metabolite identification and profiling studies in drug discovery and development pipelines.
• Quality control reference material for the analysis of finished pharmaceutical products containing Telmisartan.

Basic Information

Product Name	Telmisartan-13Cd3
CAS No.	1261396-33-1
Molecular Formula	C33H27N4O2-13Cd3
Molecular Weight	~ 518.62 g/mol (Contact for exact details)
Synonyms	4'-[(1,7'-Dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-[1,1'-biphenyl]-2-carboxylic Acid-13Cd3; Telmisartan-d3 (13C labeled); Telmisartan (methyl-d3-13C); Deuterated Telmisartan Internal Standard; Telmisartan-13C,d3; BIBR 277-13Cd3; BIBR 277 SE-13Cd3
EINECS	Contact for details

Quality Control

Every batch of Telmisartan-13Cd3 is manufactured and analyzed under strict quality systems to ensure the highest isotopic purity and chemical integrity required for sensitive mass spectrometry applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed data on isotopic enrichment, chemical purity, and identity confirmation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere if specified to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 99 atom % 13C; ≥ 98 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.