Description

Omeprazole 13Cd3 CAS NO 1261395-28-1 is a stable isotope-labeled analog of the widely used proton pump inhibitor, omeprazole, where three hydrogen atoms are replaced by deuterium (²H or D) at the 13C position. This compound is an essential internal standard for the precise and accurate quantification of omeprazole in complex biological matrices using advanced analytical techniques like LC-MS/MS. It is a critical tool for pharmaceutical R&D, bioanalytical laboratories, and contract research organizations (CROs) engaged in pharmacokinetic studies, drug metabolism research, and clinical trial support, ensuring data integrity and regulatory compliance.

Application

• Internal Standard for Bioanalysis: Primary use as a quantitative internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS/MS) for omeprazole quantification in plasma, serum, and other biological fluids.
• Pharmacokinetic and Metabolism Studies: Enables accurate tracking of drug absorption, distribution, metabolism, and excretion (ADME) in preclinical and clinical research.
• Clinical Trial Support: Critical for ensuring reliable and reproducible data in bioequivalence and therapeutic drug monitoring studies for regulatory submissions.
• Pharmaceutical R&D: Used in drug discovery and development phases to study the metabolic profile and stability of omeprazole and related compounds.
• Forensic and Toxicology Analysis: Supports accurate detection and quantification of omeprazole in forensic investigations and toxicological screenings.
• Method Development and Validation: Serves as a key reference material for developing, optimizing, and validating robust analytical methods in compliance with GLP/GCP guidelines.

Basic Information

Item	Details
Product Name	Omeprazole 13Cd3
CAS No.	1261395-28-1
Molecular Formula	C17H16D3N3O3S
Molecular Weight	Approx. 348.41 g/mol
Synonyms	5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole-13C-d3; Omeprazole-d3 (13C Labeled); Deuterated Omeprazole (13C); Omeprazole Internal Standard (13C,d3); 1H-Benzimidazole, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, 13C-d3; (RS)-Omeprazole-13C-d3; Isotopically Labeled Omeprazole
EINECS	Contact for details

Quality Control

Every batch of Omeprazole 13Cd3 is manufactured and tested under strict quality management systems. We guarantee high chemical and isotopic purity, with comprehensive characterization using NMR, HPLC, and mass spectrometry to confirm structure, isotopic enrichment, and purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results. Our quality commitment ensures the material meets the stringent requirements for use as a certified reference material in regulated bioanalytical environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified and stored in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 99.0 atom % 13C; ≥ 98.0 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.