Description

5-[4-Fluoro-3-(Trifluoromethyl)Phenyl]-2H-Tetrazole is a high-value heterocyclic building block featuring a tetrazole ring linked to a fluorinated phenyl group. This compound is critical for its role as a key intermediate in the synthesis of advanced pharmaceuticals and agrochemicals, where its unique structure imparts desirable biological activity and metabolic stability. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial synthon in the development of active pharmaceutical ingredients (APIs), particularly for drugs targeting metabolic disorders, inflammation, and central nervous system (CNS) conditions.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the tetrazole moiety.
• Material Science Research: Serves as a precursor or ligand in the development of advanced materials, including metal-organic frameworks (MOFs) and catalysts.
• Chemical Biology & Proteomics: Employed as a bioisostere for carboxylic acids or in click chemistry applications for bioconjugation and probe development.
• Organic Synthesis Building Block: Utilized in medicinal and combinatorial chemistry for constructing diverse compound libraries for high-throughput screening.

Basic Information

Product Name	5-[4-Fluoro-3-(Trifluoromethyl)Phenyl]-2H-Tetrazole
CAS No.	1261268-98-7
Molecular Formula	C8H4F4N4
Molecular Weight	232.14 g/mol
Synonyms	5-(4-Fluoro-3-(trifluoromethyl)phenyl)-1H-tetrazole; 5-(4-Fluoro-3-(trifluoromethyl)phenyl)-2H-tetrazole; 1H-Tetrazole, 5-[4-fluoro-3-(trifluoromethyl)phenyl]-; 4-Fluoro-3-(trifluoromethyl)phenyltetrazole; F-TFMP-Tetrazole
EINECS	Contact for details

Quality Control

Our production of 5-[4-Fluoro-3-(Trifluoromethyl)Phenyl]-2H-Tetrazole adheres to stringent quality management protocols. Each batch is analytically verified to meet precise customer specifications, with typical purity grades exceeding 97% (HPLC). Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to ensure full traceability and compliance with research and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.