Description

[2-Fluoro-6-(Trifluoromethoxy)Phenyl]Boronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecules through reliable cross-coupling reactions. This compound is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting CNS and inflammatory diseases.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products, leveraging the unique properties of the fluorine and trifluoromethoxy substituents.
• Liquid Crystal & OLED Material Development: Serves as a building block for constructing complex aromatic cores in electronic and display materials.
• Polymer Chemistry: Enables the incorporation of specific fluorinated aromatic units into specialty polymers for enhanced performance characteristics.
• Chemical Research & Development: A versatile synthon in academic and industrial R&D for exploring new chemical spaces and reaction methodologies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and complex target molecules for client projects.

Basic Information

Product Name	[2-Fluoro-6-(Trifluoromethoxy)Phenyl]Boronic Acid
CAS No.	1261214-72-5
Molecular Formula	C7H5BF4O3
Molecular Weight	223.92 g/mol
Synonyms	(2-Fluoro-6-(trifluoromethoxy)phenyl)boronic acid; B-[2-Fluoro-6-(trifluoromethoxy)phenyl]boronic acid; 2-Fluoro-6-(trifluoromethoxy)benzeneboronic acid; (2-Fluoro-6-(trifluoromethoxyl)phenyl)boronic acid; 2-Fluoro-6-trifluoromethoxyphenylboronic Acid; 2-Fluoro-α,α,α-trifluoro-p-cresol, 2-borono-; Boronic acid, B-[2-fluoro-6-(trifluoromethoxy)phenyl]-
EINECS	Contact for details

Quality Control

Our [2-Fluoro-6-(Trifluoromethoxy)Phenyl]Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance in regulated synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.