Description

1-(4-(Benzyloxy)-3-Methoxyphenyl)Cyclobutanecarbonitrile is a high-purity, advanced pharmaceutical intermediate with a complex, functionalized aromatic structure. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. Pharmaceutical R&D teams and fine chemical manufacturers need this material to develop and scale up production of next-generation drug candidates, where precise chemical architecture is paramount for biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug molecules, particularly those targeting the central nervous system or inflammatory pathways.
• Organic Synthesis Building Block: Used in research and development for constructing complex organic molecules via reactions involving the nitrile and aromatic ether functional groups.
• Medicinal Chemistry Research: Employed in the discovery and optimization of new chemical entities (NCEs) within pharmaceutical and biotech laboratories.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the cGMP production of clinical trial materials and commercial APIs.
• Academic Research: Utilized in university and institutional labs for methodological studies in synthetic organic chemistry and catalysis.

Basic Information

Item	Details
Product Name	1-(4-(Benzyloxy)-3-Methoxyphenyl)Cyclobutanecarbonitrile
CAS No.	1260902-74-6
Molecular Formula	C19H19NO2
Molecular Weight	293.36 g/mol
Synonyms	1-[4-(Benzyloxy)-3-methoxyphenyl]cyclobutanecarbonitrile; 4-(Benzyloxy)-3-methoxy-α-(cyclobutylidene)benzenecetonitrile; (4-Benzyloxy-3-methoxyphenyl)cyclobutanecarbonitrile; 1-(4-Benzyloxy-3-methoxyphenyl)cyclobutanecarbonitrile; Cyclobutanecarbonitrile, 1-[4-(benzyloxy)-3-methoxyphenyl]-; BOC-Protected Intermediate (context-specific); Advanced Aromatic Nitrile Intermediate
EINECS	Contact for details

Quality Control

Our production of 1-(4-(Benzyloxy)-3-Methoxyphenyl)Cyclobutanecarbonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized and released according to comprehensive in-house specifications, which typically include identity confirmation by spectroscopic methods and purity assessment by HPLC. A Certificate of Analysis (COA) detailing all relevant parameters is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.