Description

1-(Diphenylmethyl)-2-Methylazetidine-3-Carbonitrile CAS NO 1260894-65-2 is a high-purity, advanced pharmaceutical intermediate featuring a unique azetidine ring system. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of new drug candidates targeting neurological disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its constrained azetidine scaffold.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and commercial route development for potential APIs.
• Bioconjugation & Probe Development: The nitrile and azetidine functional groups can be utilized for further chemical modifications in creating biochemical probes.
• Academic & Institutional R&D: Employed in synthetic organic chemistry research to explore new reaction methodologies and heterocyclic chemistry.

Basic Information

Product Name	1-(Diphenylmethyl)-2-Methylazetidine-3-Carbonitrile
CAS No.	1260894-65-2
Molecular Formula	C18H18N2
Molecular Weight	262.35 g/mol
Synonyms	2-Methyl-1-(diphenylmethyl)azetidine-3-carbonitrile; 1-(Diphenylmethyl)-2-methyl-3-cyanoazetidine; 1-(Benzhydryl)-2-methylazetidine-3-carbonitrile; 3-Cyano-1-(diphenylmethyl)-2-methylazetidine; Azetidine-3-carbonitrile, 1-(diphenylmethyl)-2-methyl-; (2-Methyl-3-cyanoazetidin-1-yl)(diphenyl)methane
EINECS	Contact for details

Quality Control

Our 1-(Diphenylmethyl)-2-Methylazetidine-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere or in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.