Description

2-Chloro-5-(Trifluoromethoxy)Anisole is a high-value, multi-functional aromatic ether building block characterized by its unique trifluoromethoxy and chloro substituents. This compound is essential for introducing specific steric and electronic properties into target molecules, enabling the development of advanced materials and active ingredients. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical and agrochemical sectors for the synthesis of novel compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Employed as a monomer or modifier to create polymers with specific thermal, chemical, or surface properties.
• Organic Synthesis & Catalysis: Acts as a versatile building block in cross-coupling reactions and other catalytic processes for creating complex molecular architectures.
• Chemical Research (R&D): Utilized in academic and industrial laboratories for exploring new synthetic pathways and material properties.

Basic Information

Product Name	2-Chloro-5-(Trifluoromethoxy)Anisole
CAS No.	1260893-33-1
Molecular Formula	C8H6ClF3O2
Molecular Weight	226.58 g/mol
Synonyms	1-Chloro-2-methoxy-4-(trifluoromethoxy)benzene; 2-Chloro-1-methoxy-4-(trifluoromethoxy)benzene; 2-Chloro-5-(trifluoromethoxy)methoxybenzene; Anisole, 2-chloro-5-(trifluoromethoxy)-; 4-(Trifluoromethoxy)-2-chloroanisole; 2-Methoxy-5-(trifluoromethoxy)chlorobenzene
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(Trifluoromethoxy)Anisole is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including GC/HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.