Description

4-Bromo-3-Chloro-2-Fluorobenzotrifluoride is a high-value, multi-halogenated aromatic building block, specifically engineered for advanced synthetic chemistry. Its unique trifluoromethyl and halogen substitution pattern makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where precise molecular architecture is required for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, leveraging the stability imparted by the trifluoromethyl group.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Functional Material Development: Employed in creating specialty polymers, ligands for catalysis, and advanced organic frameworks with specific electronic characteristics.
• Cross-Coupling Reactions: The bromo and chloro substituents provide orthogonal reactivity for sequential Suzuki, Stille, or Buchwald-Hartwig amination reactions.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and material science research programs exploring structure-activity relationships.

Basic Information

Product Name	4-Bromo-3-Chloro-2-Fluorobenzotrifluoride
CAS No.	1260890-50-3
Molecular Formula	C7H2BrClF4
Molecular Weight	277.44 g/mol
Synonyms	1-Bromo-2-chloro-3-fluoro-4-(trifluoromethyl)benzene; 2-Fluoro-3-chloro-4-bromobenzotrifluoride; 4-Bromo-3-chloro-2-fluoro-α,α,α-trifluorotoluene; 3-Chloro-4-bromo-2-fluorobenzotrifluoride; Benzene, 1-bromo-2-chloro-3-fluoro-4-(trifluoromethyl)-; BCFBTF
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-3-Chloro-2-Fluorobenzotrifluoride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for sensitive R&D and scale-up processes. A detailed Certificate of Analysis (COA), including results from HPLC, GC, NMR, and mass spectrometry, is supplied with each shipment to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.