Description

3,5-Difluoro-4-Nitrobenzamide is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the strategic placement of fluorine and nitro groups, which are crucial for modulating the electronic properties, lipophilicity, and metabolic stability of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and antibacterial programs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the difluoro-nitro motif contributes to biological activity.
• Material Science Research: Serves as a precursor for the synthesis of specialty polymers and liquid crystals with unique electronic properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic aromatic substitution, and reduction reactions to create complex, fluorinated aromatic systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.

Basic Information

Product Name	3,5-Difluoro-4-Nitrobenzamide
CAS No.	1260882-93-6
Molecular Formula	C7H4F2N2O3
Molecular Weight	202.12 g/mol
Synonyms	4-Nitro-3,5-difluorobenzamide; 3,5-Difluoro-4-nitrobenzamide; Benzamide, 3,5-difluoro-4-nitro-; 1260882-93-6; AI3-63500; AKOS040759626; BDBM50382835; CTK8G7535; FT-0772324; NSC 405124; SCHEMBL21821077
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-4-Nitrobenzamide is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and research-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.