Description

2-(2-Bromoethyl)-1,3,5-Trifluorobenzene is a high-value, multi-functional aromatic building block that combines a reactive bromoethyl side chain with a trifluoromethyl-substituted benzene core. This compound matters for its unique reactivity profile, enabling precise molecular construction in advanced synthetic pathways. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atoms and bromoethyl handle contribute to biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors or liquid crystals, where fluorinated aromatics are critical.
• Cross-Coupling Reactions: The bromoethyl moiety acts as an excellent electrophile in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Fluorine Chemistry Studies: A valuable substrate for investigating the effects of fluorine substitution on aromatic reactivity and physical properties.

Basic Information

Item	Detail
Product Name	2-(2-Bromoethyl)-1,3,5-Trifluorobenzene
CAS No.	1260853-47-1
Molecular Formula	C8H6BrF3
Molecular Weight	239.04 g/mol
Synonyms	1-(2-Bromoethyl)-3,5-Difluorobenzene (common misnomer); 2-Bromoethyl-1,3,5-Trifluorobenzene; 1,3,5-Trifluoro-2-(2-bromoethyl)benzene; (2-Bromoethyl)trifluorobenzene; α-Bromo-2,4,6-trifluorophenylethane; 2,4,6-Trifluoro-β-bromoethylbenzene; Benzene, 1-(2-bromoethyl)-3,5-difluoro-; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Every batch of 2-(2-Bromoethyl)-1,3,5-Trifluorobenzene is produced and tested under a strict quality management system. We ensure high purity and batch-to-batch consistency through advanced analytical techniques including GC, HPLC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.