Description

3-Bromo-4-(Pyrrolidin-1-Yl)Benzonitrile is a high-purity, advanced pharmaceutical intermediate featuring a benzonitrile core substituted with bromine and a pyrrolidine group. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and exploring new chemical spaces.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its heterocyclic structure.
• Chemical Biology Probe Synthesis: Serves as a versatile scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science Research: Investigated as a monomer or building block for specialty polymers and organic electronic materials due to its aromatic and nitrile functionality.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	3-Bromo-4-(Pyrrolidin-1-Yl)Benzonitrile
CAS No.	1260837-23-7
Molecular Formula	C11H11BrN2
Molecular Weight	251.12 g/mol
Synonyms	4-(Pyrrolidin-1-yl)-3-bromobenzonitrile; 3-Bromo-4-pyrrolidin-1-ylbenzonitrile; 3-Bromo-4-(1-pyrrolidinyl)benzonitrile; Benzonitrile, 3-bromo-4-(1-pyrrolidinyl)-; 1260837-23-7; 3-Bromo-4-pyrrolidinobenzonitrile
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-(Pyrrolidin-1-Yl)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.