Description

Benzene, 2-Chloro-1-Ethynyl-4-Nitro- CAS NO 1260829-25-1 is a specialized nitro-substituted aromatic acetylene derivative, serving as a high-value synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both an electron-withdrawing nitro group and a reactive ethynyl moiety, makes it a critical building block for constructing complex molecular architectures. This compound is primarily utilized by research institutions and industrial R&D departments focused on developing novel pharmaceuticals, agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Agrochemical Research: Building block for developing new generation herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science: Used in the research and development of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Versatile intermediate for Suzuki, Sonogashira, and other cross-coupling reactions to create complex conjugated systems.
• Dye & Pigment Industry: Serves as a precursor for synthesizing specialized nitroaromatic dyes and pigments.
• Academic & Contract Research: Essential reagent for methodological studies and discovery chemistry in academic and CRO laboratories.

Basic Information

Product Name	Benzene, 2-Chloro-1-Ethynyl-4-Nitro-
CAS No.	1260829-25-1
Molecular Formula	C8H4ClNO2
Molecular Weight	181.58 g/mol
Synonyms	2-Chloro-1-ethynyl-4-nitrobenzene; 1-Chloro-2-ethynyl-5-nitrobenzene; 4-Nitro-2-chlorophenylacetylene; (2-Chloro-4-nitrophenyl)ethyne; 2-Chloro-4-nitrobenzeneacetylene; 1-Ethynyl-2-chloro-4-nitrobenzene; 2-Chloro-4-nitrophenylacetylene
EINECS	Contact for details

Quality Control

Every batch of Benzene, 2-Chloro-1-Ethynyl-4-Nitro- is produced and tested under strict quality management protocols to ensure consistency and purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, identity confirmation, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for traceability and reliability, ensuring the material meets the exacting requirements of advanced synthetic chemistry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.