Description

3,3,3-Trifluoro-n-Methoxy-n-Methylpropanamide is a specialized fluorinated amide building block of significant interest in advanced organic synthesis. Its unique structure, featuring a trifluoromethyl group and a methoxy-methyl amide moiety, makes it a valuable precursor for introducing fluorine-containing motifs into target molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries. It serves as a key intermediate in the synthesis of novel active ingredients where the trifluoromethyl group can enhance metabolic stability, lipophilicity, and bioavailability.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the CF₃ group improves efficacy and environmental profile.
• Advanced Material Precursor: Serves as a monomer or modifier in the development of specialty polymers and coatings with unique surface properties and chemical resistance.
• Ligand and Catalyst Development: Employed in the creation of novel fluorinated ligands for catalysis and molecular recognition applications.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research exploring new methodologies for C-F bond formation and functional group transformations.

Basic Information

Product Name	3,3,3-Trifluoro-n-Methoxy-n-Methylpropanamide
CAS No.	1260812-72-3
Molecular Formula	C₆H₁₀F₃NO₂
Molecular Weight	185.15 g/mol
Synonyms	3,3,3-Trifluoro-N-methoxy-N-methylpropanamide; N-Methoxy-N-methyl-3,3,3-trifluoropropanamide; 3,3,3-Trifluoropropanoic Acid N-Methoxy-N-Methylamide; N-Methoxy-N-methyl-3,3,3-trifluoropropionamide; 3,3,3-Trifluoro-N-methoxy-N-methylpropionamide; TFMMPA; Weinreb Amide of 3,3,3-Trifluoropropanoic Acid
EINECS	Contact for details

Quality Control

Our 3,3,3-Trifluoro-n-Methoxy-n-Methylpropanamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and reliability for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.