Description

5-Bromo-3-Chloro-2-Hydroxy-Benzonitrile is a versatile halogenated benzonitrile derivative that serves as a critical synthetic intermediate. Its unique substitution pattern makes it a valuable building block for constructing complex molecules in advanced chemical synthesis. This compound is primarily utilized by research institutions and industrial R&D departments focused on developing novel agrochemicals, pharmaceuticals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic scaffolds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its bioactive halogen and nitrile functional groups.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a molecular probe or tagging reagent due to its reactive phenolic and nitrile moieties.
• Organic Synthesis Building Block: A versatile substrate for cross-coupling reactions, nucleophilic aromatic substitution, and cyano group transformations.

Basic Information

Product Name	5-Bromo-3-Chloro-2-Hydroxy-Benzonitrile
CAS No.	1260810-06-7
Molecular Formula	C7H3BrClNO
Molecular Weight	232.46 g/mol
Synonyms	2-Hydroxy-5-bromo-3-chlorobenzonitrile; 3-Chloro-5-bromo-2-hydroxybenzonitrile; 5-Bromo-3-chlorosalicylonitrile; 2-Cyano-4-bromo-6-chlorophenol; Benzonitrile, 5-bromo-3-chloro-2-hydroxy-; 1260810-06-7
EINECS	Contact for details

Quality Control

Our production of 5-Bromo-3-Chloro-2-Hydroxy-Benzonitrile adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.