Description

Ethyl 1-(2-Fluoro-5-(Trifluoromethyl)Benzyl)-1H-Imidazole-4-Carboxylate is a high-value, multi-fluorinated heterocyclic building block designed for advanced synthetic chemistry. This compound is critical for research and development in life sciences, serving as a key intermediate in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is essential for medicinal chemists and process development scientists in pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate complex, fluorinated imidazole motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, particularly in oncology, antiviral, and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the fluorinated benzyl-imidazole structure confers enhanced biological activity and stability.
• Chemical Biology Probe Development: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with tailored electronic or surface properties.
• Custom Synthesis & Contract Manufacturing: A key starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	Ethyl 1-(2-Fluoro-5-(Trifluoromethyl)Benzyl)-1H-Imidazole-4-Carboxylate
CAS No.	1260789-05-6
Molecular Formula	C14H12F4N2O2
Molecular Weight	316.25 g/mol
Synonyms	1-[(2-Fluoro-5-(trifluoromethyl)phenyl)methyl]-1H-imidazole-4-carboxylic acid ethyl ester; Ethyl 1-[[2-fluoro-5-(trifluoromethyl)phenyl]methyl]imidazole-4-carboxylate; 4-Carbethoxy-1-(2-fluoro-5-trifluoromethylbenzyl)imidazole; 1-(2-Fluoro-5-trifluoromethylbenzyl)-1H-imidazole-4-carboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 1-(2-Fluoro-5-(Trifluoromethyl)Benzyl)-1H-Imidazole-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.