Description

(3-Fluorocyclobutyl)Methanol CAS NO 1260654-20-3 is a versatile fluorinated building block of significant interest in advanced organic synthesis. Its unique structure, featuring a fluorinated cyclobutane ring, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, metabolic diseases, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom can enhance bioavailability and stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the creation of specialty polymers and advanced materials where fluorinated moieties impart unique chemical resistance or surface properties.
• Fluorine Chemistry Research: An important reagent for academic and industrial research exploring new methodologies in fluorination and cyclobutane chemistry.

Basic Information

Product Name	(3-Fluorocyclobutyl)Methanol
CAS No.	1260654-20-3
Molecular Formula	C5H9FO
Molecular Weight	104.12 g/mol
Synonyms	(3-Fluorocyclobutyl)methanol; 3-Fluorocyclobutanemethanol; (3-Fluorocyclobutyl)carbinol; 1-(Hydroxymethyl)-3-fluorocyclobutane; 3-Fluorocyclobutylmethyl alcohol; Fluorocyclobutylmethanol; FCB-OH (common abbreviation)
EINECS	Contact for details

Quality Control

Our (3-Fluorocyclobutyl)Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.