Description

1-(2-Chloro-4-Fluorophenyl)Cyclopropane-1-Carbonitrile is a versatile and high-value organic intermediate featuring a cyclopropane ring substituted with a nitrile group and a halogenated aromatic system. This unique structure makes it a critical building block for the synthesis of complex molecules in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-inflammatory agents, and enzyme inhibitors.
• Agrochemical Synthesis: Serves as a crucial building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used in organometallic chemistry to create specialized ligands for catalytic systems and materials science applications.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for electronics and advanced materials.
• Academic and Industrial R&D: A valuable reagent for method development and exploring new chemical spaces in synthetic organic chemistry laboratories.

Basic Information

Product Name	1-(2-Chloro-4-Fluorophenyl)Cyclopropane-1-Carbonitrile
CAS No.	1260650-46-1
Molecular Formula	C10H7ClFN
Molecular Weight	195.62 g/mol
Synonyms	1-(2-Chloro-4-fluorophenyl)cyclopropanecarbonitrile; 2-Chloro-4-fluorophenylcyclopropanecarbonitrile; Cyclopropanecarbonitrile, 1-(2-chloro-4-fluorophenyl)-; 1-(2-Chloro-4-fluorophenyl)cyclopropanecarbonitrile; (2-Chloro-4-fluorophenyl)cyclopropanecarbonitrile
EINECS	Contact for details

Quality Control

Our production of 1-(2-Chloro-4-Fluorophenyl)Cyclopropane-1-Carbonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR) to confirm identity and quantify purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.