Description

2-Bromo-6-Piperidinobenzonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its brominated benzonitrile core and piperidine substituent. This compound is of significant value for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in drug discovery programs, particularly those focused on kinase inhibitors and central nervous system (CNS) targeting agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates, especially in oncology and neurological disorder research.
• Medicinal Chemistry Building Block: Used in structure-activity relationship (SAR) studies and lead optimization due to its modifiable bromine and nitrile functional groups.
• Kinase Inhibitor Development: Serves as a core scaffold for designing and synthesizing novel small-molecule kinase inhibitors.
• Chemical Biology Research: Employed in the development of chemical probes to study specific biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for exploratory organic synthesis and method development.

Basic Information

Item	Details
Product Name	2-Bromo-6-Piperidinobenzonitrile
CAS No.	1260649-11-3
Molecular Formula	C12H13BrN2
Molecular Weight	265.15 g/mol
Synonyms	6-Piperidino-2-bromobenzonitrile; 2-Bromo-6-(piperidin-1-yl)benzonitrile; 2-Bromo-6-piperidin-1-ylbenzonitrile; 1-(3-Bromo-2-cyanophenyl)piperidine; Benzonitrile, 2-bromo-6-(1-piperidinyl)-; 1260649-11-3
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Piperidinobenzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry guidelines for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.