Description

(2S)-2-Amino-2-Benzo[D]Furan-2-Ylacetic Acid CAS NO 1260619-54-2 is a high-purity chiral amino acid derivative featuring a benzo[b]furan scaffold. This compound serves as a critical chiral building block and intermediate in advanced pharmaceutical synthesis, enabling the development of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), especially for projects requiring enantiomerically pure, structurally complex intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new chemical entities (NCEs) and Active Pharmaceutical Ingredients (APIs).
• Asymmetric Synthesis: Used as a starting material or reagent in stereoselective synthesis to construct complex molecules with defined chirality.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Peptidomimetics: Incorporated into peptide analogs and mimetics to enhance metabolic stability and bioavailability.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds or probes for studying biological pathways and target engagement.
• Contract Development and Manufacturing (CDMO): Supplied to CDMOs for scale-up synthesis under cGMP conditions for clinical trial material production.

Basic Information

Product Name	(2S)-2-Amino-2-Benzo[D]Furan-2-Ylacetic Acid
CAS No.	1260619-54-2
Molecular Formula	C₁₀H₉NO₃
Molecular Weight	191.18 g/mol
Synonyms	(S)-2-Amino-2-(benzo[b]furan-2-yl)acetic acid; (S)-2-(Benzofuran-2-yl)glycine; L-2-(Benzofuran-2-yl)glycine; 2-(Benzofur-2-yl)-L-glycine; (2S)-2-Amino-2-(1-benzofuran-2-yl)acetic acid; (S)-α-Amino-1-benzofuran-2-acetic acid; BFA; Benzo[b]furan-2-yl-L-glycine
EINECS	Contact for details

Quality Control

Our (2S)-2-Amino-2-Benzo[D]Furan-2-Ylacetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.