Description

Cyclohexanepropanoic Acid, β-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (βs)- is a high-purity, non-natural amino acid derivative featuring the Fmoc (9-fluorenylmethoxycarbonyl) protecting group. This compound is critical for solid-phase peptide synthesis (SPPS), where it serves as a key building block for introducing specific structural motifs into peptide chains. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, peptidomimetics, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): As an Fmoc-protected amino acid derivative for the automated or manual synthesis of custom peptides.
• Pharmaceutical R&D: Incorporation into peptide-based drug candidates to modulate bioavailability, stability, and receptor binding affinity.
• Bioconjugation: Serving as a specialized linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or reporter molecules.
• Chemical Biology: Used in the study of protein-protein interactions and the development of enzyme inhibitors or activators.
• Material Science: Potential use in creating peptide-functionalized polymers or surfaces with specific biological activities.

Basic Information

Product Name	Cyclohexanepropanoic Acid, β-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (βs)-
CAS No.	1260614-86-5
Molecular Formula	C24H27NO4
Molecular Weight	393.48 g/mol
Synonyms	Fmoc-β-(3-cyclohexyl)-L-alanine; Fmoc-β-cyclohexyl-L-alanine; (S)-3-Cyclohexyl-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)propanoic acid; (S)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-cyclohexylpropanoic acid; Fmoc-β-Cha-OH; Fmoc-3-cyclohexyl-L-alanine; Fmoc-(S)-3-cyclohexylalanine; Fmoc-L-β-cyclohexylalanine
EINECS	Contact for details

Quality Control

Our Cyclohexanepropanoic Acid, β-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (βs)- is manufactured under strict quality management systems to ensure the high purity and consistency required for sensitive synthetic applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles. We support compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.