Description

Moexiprilat Acyl--D-Glucuronide, >65% is a key metabolite and reference standard of the ACE inhibitor moexipril. This high-purity compound is essential for pharmaceutical research and development, particularly in the study of drug metabolism and pharmacokinetics (DMPK). It is primarily used by analytical laboratories, contract research organizations (CROs), and pharmaceutical companies engaged in bioanalytical method development, metabolite identification, and regulatory compliance testing.

Application

• Pharmaceutical Reference Standard: Serves as a certified standard for the quantitative and qualitative analysis of moexipril and its metabolites in biological matrices.
• Drug Metabolism & Pharmacokinetics (DMPK) Studies: Critical for investigating the metabolic pathways, clearance mechanisms, and bioavailability of moexipril.
• Bioanalytical Method Development: Used to develop and validate sensitive HPLC, LC-MS, or LC-MS/MS methods for pharmacokinetic studies.
• Impurity Profiling and Characterization: Aids in identifying and quantifying process-related or degradation impurities in active pharmaceutical ingredient (API) batches.
• Regulatory Submission Support: Provides essential data for regulatory filings (e.g., FDA, EMA) requiring detailed metabolite safety and characterization.
• Clinical Research: Supports studies monitoring drug and metabolite levels in plasma or urine during clinical trials.

Basic Information

Product Name	Moexiprilat Acyl--D-Glucuronide, >65%
CAS No.	1260613-88-4
Molecular Formula	C28H38N2O14
Molecular Weight	626.61 g/mol
Synonyms	Moexiprilat Glucuronide; Moexipril Acyl Glucuronide; (3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic acid 1-(β-D-Glucopyranuronosyl) ester; Moexipril Metabolite; UNII-5G2F6C6Q4C
EINECS	Contact for details

Quality Control

Our Moexiprilat Acyl--D-Glucuronide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity confirmation and identity verification by spectroscopic methods (IR, NMR, MS). We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with relevant standards for pharmaceutical reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, moisture-free environment. This hygroscopic and light-sensitive compound should be allowed to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	> 65%
Water Content (KF)	< 5.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.