Description

Cyclopentanepropanoic Acid, β-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (βs)- is a high-purity, non-natural amino acid derivative featuring the Fmoc-protecting group, essential for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring precise stereochemical control and high coupling efficiency in solid-phase peptide synthesis (SPPS) workflows. It is primarily utilized by the pharmaceutical, biotechnology, and academic research sectors for the development of novel therapeutic peptides, peptidomimetics, and complex bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key Fmoc-protected building block for the sequential assembly of custom peptide sequences.
• Pharmaceutical Research & Development: Used in the discovery and synthesis of peptide-based drug candidates, including hormone analogs and enzyme inhibitors.
• Peptidomimetic Design: Incorporates the cyclopentane moiety to introduce conformational constraints, enhancing metabolic stability and receptor selectivity.
• Bioconjugation: Acts as a specialized linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or carriers.
• Combinatorial Chemistry Libraries: Employed to create diverse libraries of cyclic or constrained peptides for high-throughput screening.
• Academic & Process Chemistry: A valuable reagent for methodological studies in organic synthesis and for scaling up peptide manufacturing processes.

Basic Information

Product Name	Cyclopentanepropanoic Acid, β-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (βs)-
CAS No.	1260609-14-0
Molecular Formula	C22H23NO4
Molecular Weight	365.42 g/mol
Synonyms	(3S)-3-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]cyclopentanepropanoic Acid; Fmoc-β-homoCyp-OH; Fmoc-(S)-3-Amino-1-cyclopentanepropionic Acid; Fmoc-β-Homocyclopentyl-Ala-OH; (S)-3-(Fmoc-amino)cyclopentanepropanoic Acid; N-α-Fmoc-β-homocyclopentylalanine; N-Fmoc-β-homocyclopentyl-L-alanine; β-HOMOCYCLOPENTYLALANINE FMOC
EINECS	Contact for details

Quality Control

Our Cyclopentanepropanoic Acid, β-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (βs)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and peptide synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.