Description

n-Fmoc-(S)-4-Fluorohomophenylalanine is a high-purity, non-natural amino acid derivative designed for advanced peptide synthesis. This compound is a critical building block in the development of novel peptide-based pharmaceuticals and research tools, offering precise stereochemical control and chemical functionality. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers specializing in peptide drug discovery and development.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the automated synthesis of complex peptides, particularly those requiring fluorinated aromatic side chains.
• Pharmaceutical Intermediate: Used in the research and production of active pharmaceutical ingredients (APIs) for therapeutic peptides targeting metabolic disorders, oncology, and CNS diseases.
• Peptidomimetic Development: Serves as a precursor for creating stable peptide analogs with enhanced bioavailability and receptor selectivity.
• Chemical Biology Probes: Incorporated into labeled peptides for studying protein-protein interactions, enzyme activity, and cellular uptake mechanisms.
• Library Synthesis: Employed in combinatorial chemistry to generate diverse peptide libraries for high-throughput screening in drug discovery campaigns.
• Academic Research: A valuable reagent for university and institutional labs investigating peptide structure-activity relationships and novel synthetic methodologies.

Basic Information

Product Name	n-Fmoc-(S)-4-Fluorohomophenylalanine
CAS No.	1260608-85-2
Molecular Formula	C25H22FNO4
Molecular Weight	419.45 g/mol
Synonyms	Fmoc-4-F-homoPhe-OH; Fmoc-(S)-4-fluoro-homophenylalanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-fluoro-L-homophenylalanine; (2S)-2-[(9H-Fluoren-9-ylmethoxy)formamido]-4-(4-fluorophenyl)butanoic acid; Fmoc-L-4-fluorohomophenylalanine; N-Fmoc-4-fluoro-L-homophenylalanine; 4-Fluoro-L-homophenylalanine, N-Fmoc derivative; BOC Sciences Brand Product BLD-1260608-85-2
EINECS	Contact for details

Quality Control

Our n-Fmoc-(S)-4-Fluorohomophenylalanine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive pharmaceutical research. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles. We adhere to relevant industry guidelines to support our customers' regulatory and documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.