Description

n-Fmoc-R-3-Chlorophenylglycine CAS NO 1260590-39-3 is a high-purity, non-natural amino acid derivative designed for advanced peptide synthesis. This compound is a critical building block in the development of complex peptide-based pharmaceuticals and research tools, offering precise stereochemical control. It is essential for medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and life science research sectors who require reliable, high-quality intermediates for solid-phase peptide synthesis (SPPS).

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the automated synthesis of therapeutic peptides and peptidomimetics.
• Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, particularly in oncology and metabolic disease research.
• Peptidomimetic Design: Incorporation of the 3-chlorophenyl side chain introduces unique steric and electronic properties for structure-activity relationship (SAR) studies.
• Combinatorial Chemistry Libraries: Serves as a valuable component for generating diverse compound libraries for high-throughput screening.
• Bioconjugation: Can be used in the synthesis of peptide tags and linkers for antibody-drug conjugates (ADCs) or diagnostic probes.
• Academic & Institutional Research: Fundamental research in biochemistry, chemical biology, and organic synthesis methodologies.

Basic Information

Product Name	n-Fmoc-R-3-Chlorophenylglycine
CAS No.	1260590-39-3
Molecular Formula	C23H18ClNO4
Molecular Weight	407.85 g/mol
Synonyms	Fmoc-3-chloro-D-homophenylglycine; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(3-chlorophenyl)acetic acid; Fmoc-(R)-3-chloro-homoPhg-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-chloro-D-homophenylglycine; Fmoc-D-3-chlorohomophenylglycine; N-Fmoc-3-chloro-D-homophenylglycine; BOC Sciences Brand Name: BBL-BB-01466
EINECS	Contact for details

Quality Control

Our n-Fmoc-R-3-Chlorophenylglycine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with research and development standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and should be handled under standard laboratory conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.