Description

Benzenebutanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-4-Methyl-, (αs)- is a high-purity, non-natural amino acid derivative featuring a fluorenylmethyloxycarbonyl (Fmoc) protecting group. This compound matters as a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled assembly of complex peptides and proteins for research and therapeutic development. It is primarily needed by pharmaceutical R&D teams, biotechnology companies, and academic laboratories focused on peptide chemistry, drug discovery, and proteomics.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key Fmoc-protected amino acid precursor for the automated synthesis of custom peptides.
• Pharmaceutical Intermediate: Used in the research and development of novel peptide-based therapeutics and active pharmaceutical ingredients (APIs).
• Bioconjugation: Acts as a specialized linker or spacer molecule for attaching peptides to other biomolecules, surfaces, or carriers.
• Chemical Biology Research: Employed in studies exploring protein-protein interactions, enzyme substrates, and signal transduction pathways.
• Combinatorial Chemistry Libraries: A valuable component for generating diverse libraries of compounds for high-throughput screening.
• Academic & Institutional Research: Supports fundamental studies in organic synthesis, medicinal chemistry, and biochemistry.

Basic Information

Product Name	Benzenebutanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-4-Methyl-, (αs)-
CAS No.	1260587-57-2
Molecular Formula	C26H25NO4
Molecular Weight	415.48 g/mol
Synonyms	Fmoc-4-methyl-DL-phenylalanine; Fmoc-4-Me-Phe-OH; (αS)-α-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-4-methylbenzenebutanoic acid; Fmoc-4-methylphenylalanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-methyl-DL-phenylalanine; Fmoc-4-methyl-DL-homophenylalanine; Fmoc-4-Me-homoPhe-OH; 4-Methyl-DL-phenylalanine, N-Fmoc derivative
EINECS	Contact for details

Quality Control

Our Benzenebutanoic Acid, α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-4-Methyl-, (αs)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.