Description

2-Ethoxy-4-Trifluoromethylphenylboronic Acid is a specialized organoboron compound that serves as a critical building block in modern synthetic chemistry. Its value lies in enabling the precise construction of complex molecules through efficient cross-coupling reactions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and fungicides, leveraging the trifluoromethyl group for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs and semiconductors, where the boronic acid functionality allows for precise molecular assembly.
• Chemical Biology Probes: Utilized to create labeled compounds and probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP conditions.

Basic Information

Product Name	2-Ethoxy-4-Trifluoromethylphenylboronic Acid
CAS No.	1260518-74-8
Molecular Formula	C9H10BF3O3
Molecular Weight	233.98 g/mol
Synonyms	(2-Ethoxy-4-(trifluoromethyl)phenyl)boronic Acid; 2-Ethoxy-α,α,α-trifluoro-p-tolylboronic Acid; 4-Trifluoromethyl-2-ethoxyphenylboronic Acid; B-[2-Ethoxy-4-(trifluoromethyl)phenyl]boronic Acid; 2-Ethoxy-4-trifluoromethylbenzeneboronic Acid; 2-Ethoxy-4-(trifluoromethyl)benzeneboronic Acid
EINECS	Contact for details

Quality Control

Our 2-Ethoxy-4-Trifluoromethylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with stringent industry specifications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.