Description

4-Chloro-7-Fluoro-1-Indanone is a high-purity fluorinated and chlorinated indanone derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in its unique halogenated structure, which is essential for constructing complex molecules with targeted biological activity. This compound is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting specific enzyme pathways.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex heterocyclic compounds and exploring structure-activity relationships (SAR).
• Agrochemical Development: Serves as a precursor in the research and synthesis of new-generation herbicides and pesticides with enhanced efficacy.
• Material Science: Investigated as a monomer or precursor for specialty polymers and advanced organic electronic materials.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	4-Chloro-7-Fluoro-1-Indanone
CAS No.	1260018-63-0
Molecular Formula	C9H6ClFO
Molecular Weight	184.60 g/mol
Synonyms	1-Indanone, 4-chloro-7-fluoro-; 4-Chloro-7-fluoroindan-1-one; 7-Fluoro-4-chloro-1-indanone; 4-Chloro-7-fluoro-2,3-dihydro-1H-inden-1-one; 1260018-63-0; FC-ICL; 4,7-Dihalo-1-indanone
EINECS	Contact for details

Quality Control

Our 4-Chloro-7-Fluoro-1-Indanone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications. Our production adheres to cGMP guidelines where applicable, supporting its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.