Description

Boc-3,5-Diiodo-Dl-Tyrosine is a protected, iodinated derivative of the amino acid tyrosine, widely used as a key synthetic intermediate in advanced organic and peptide chemistry. Its primary value lies in enabling the controlled introduction of the tyrosine moiety into complex molecular architectures, particularly where the iodine atoms serve as versatile handles for further functionalization via cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, specifically for the development of novel peptide-based therapeutics, radiopharmaceuticals, and molecular probes.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel peptide drugs and bioactive compounds.
• Radiopharmaceutical Precursor: Serves as a precursor for radioiodinated compounds used in medical imaging and targeted radiotherapy.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate modified tyrosine residues.
• Chemical Biology Research: Employed in the development of molecular probes and activity-based protein profiling agents.
• Cross-Coupling Reactions: The iodine atoms provide sites for palladium-catalyzed reactions (e.g., Suzuki, Sonogashira) to create complex biaryl structures.
• Protecting Group Strategy: The tert-butoxycarbonyl (Boc) group allows for orthogonal protection in multi-step synthetic sequences.

Basic Information

Product Name	Boc-3,5-Diiodo-Dl-Tyrosine
CAS No.	1260011-49-1
Molecular Formula	C₁₄H₁₇I₂NO₅
Molecular Weight	533.10 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-3,5-diiodo-DL-tyrosine; Boc-Tyr(3,5-I2)-OH; DL-3,5-Diiodotyrosine N-Boc derivative; 2-((tert-Butoxycarbonyl)amino)-3-(3,5-diiodo-4-hydroxyphenyl)propanoic acid; tert-Butyl (3,5-diiodo-4-hydroxyphenethyl)carbamate; BOC-DL-Tyr(3,5-I2); N-Boc-3,5-diiodotyrosine
EINECS	Contact for details

Quality Control

Every batch of Boc-3,5-Diiodo-Dl-Tyrosine is manufactured and tested under a strict quality management system. We ensure compliance with high-purity standards suitable for research and pharmaceutical development. Comprehensive analytical testing, including HPLC for purity and identity confirmation, is performed. A Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.