Description

4-Fluoro-2-Trifluoromethyl-Dl-Phenylalanine, 97% is a fluorinated derivative of the amino acid phenylalanine, characterized by its trifluoromethyl and fluorine substituents which impart unique electronic and steric properties. This compound is a critical pharmaceutical intermediate and building block for advanced organic synthesis, enabling the development of novel bioactive molecules. It is primarily utilized by research institutions and chemical manufacturers in the pharmaceutical, agrochemical, and material science sectors for drug discovery and the synthesis of complex fluorinated compounds.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Peptidomimetics & Proteomics: Serves as a modified amino acid residue in the design of peptide analogs and probes for biochemical studies.
• Material Science Precursor: Employed in the synthesis of specialty polymers and liquid crystals, leveraging its fluorinated aromatic system.
• Chemical Biology Tool: Acts as a substrate or inhibitor in enzymatic studies to investigate fluorine's role in protein-ligand interactions.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions and as a precursor for more complex trifluoromethylated aromatic compounds.

Basic Information

Product Name	4-Fluoro-2-Trifluoromethyl-Dl-Phenylalanine, 97%
CAS No.	1259997-93-7
Molecular Formula	C₁₀H₉F₄NO₂
Molecular Weight	251.18 g/mol
Synonyms	DL-4-Fluoro-2-(trifluoromethyl)phenylalanine; 2-Amino-3-[4-fluoro-2-(trifluoromethyl)phenyl]propanoic acid; (±)-4-Fluoro-α-methyl-2-(trifluoromethyl)benzenepropanoic acid; 4-Fluoro-2-trifluoromethylphenylalanine; F-Tfm-Phe; 4-F-2-CF3-DL-Phe; 4-Fluoro-2-(trifluoromethyl)-DL-phenylalanine
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-Trifluoromethyl-Dl-Phenylalanine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with the stated specifications. We support cGMP standards for pharmaceutical applications and can provide regulatory support documentation upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Optical Purity (Chiral HPLC)	DL-Racemate
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.