Description

2-Fluoro-3-(Trifluoromethyl)-Dl-Phenylalanine is a fluorinated derivative of the amino acid phenylalanine, distinguished by its trifluoromethyl and fluorine substituents. This compound is a critical building block in medicinal chemistry, where its unique structure is leveraged to modulate the potency, metabolic stability, and bioavailability of target molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and peptide-based therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in oncology and CNS disorders.
• Peptide Modification: Used to incorporate fluorinated amino acid residues into peptides to enhance their stability against enzymatic degradation and alter their physicochemical properties.
• Agrochemical Research: Serves as a precursor in the synthesis of advanced, fluorinated agrochemicals with potentially improved activity and environmental profiles.
• Proteomics & Biochemical Tool: Employed in the study of enzyme mechanisms and protein interactions where fluorine acts as a spectroscopic or steric probe.
• Material Science: Exploration into fluorinated organic compounds for advanced polymers or liquid crystals with specific electronic or surface properties.

Basic Information

Product Name	2-Fluoro-3-(Trifluoromethyl)-Dl-Phenylalanine
CAS No.	1259993-82-2
Molecular Formula	C₁₀H₉F₄NO₂
Molecular Weight	251.18 g/mol
Synonyms	DL-2-Fluoro-3-(trifluoromethyl)phenylalanine; (±)-2-Amino-3-[2-fluoro-3-(trifluoromethyl)phenyl]propanoic acid; 3-(2-Fluoro-3-(trifluoromethyl)phenyl)-DL-alanine; 2-Fluoro-3-trifluoromethyl-DL-phenylalanine; F3C-Phe(2-F)-OH (DL); (RS)-2-Amino-3-(2-fluoro-3-(trifluoromethyl)phenyl)propanoic acid; α-Amino-2-fluoro-3-(trifluoromethyl)benzenepropanoic acid (racemic)
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-3-(Trifluoromethyl)-Dl-Phenylalanine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.