Description

2,3,4-Trifluoro-Dl-Phenylalanine is a fluorinated derivative of the essential amino acid phenylalanine, distinguished by its unique trifluoro substitution pattern. This structural modification is critical for enhancing metabolic stability and altering the physicochemical properties of bioactive molecules, making it a valuable building block in advanced research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams for the synthesis of novel compounds where fluorine introduction is a key design strategy.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of fluorinated drug candidates, including protease inhibitors and enzyme modulators.
• Agrochemical Research: Used in the synthesis of novel herbicides and pesticides, where fluorine atoms can improve lipophilicity and biological activity.
• Peptide Chemistry: Serves as a modified amino acid residue for constructing fluorinated peptides to study structure-activity relationships and enhance peptide stability.
• Biochemical Probe Development: Employed in creating labeled analogs and probes for metabolic pathway studies and imaging applications.
• Material Science: Potential precursor for specialty polymers and advanced materials requiring fluorinated aromatic components.

Basic Information

Product Name	2,3,4-Trifluoro-Dl-Phenylalanine
CAS No.	1259978-34-1
Molecular Formula	C9H8F3NO2
Molecular Weight	219.16 g/mol
Synonyms	DL-2,3,4-Trifluorophenylalanine; (±)-2,3,4-Trifluoro-DL-phenylalanine; 2,3,4-Trifluoro-DL-α-aminohydrocinnamic acid; (RS)-2-Amino-3-(2,3,4-trifluorophenyl)propanoic acid; 2,3,4-Trifluoro-DL-β-phenylalanine; 3-(2,3,4-Trifluorophenyl)-DL-alanine; NSC 87680; 2,3,4-Trifluoro-DL-Phe
EINECS	Contact for details

Quality Control

Our 2,3,4-Trifluoro-Dl-Phenylalanine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	DL-mixture (Racemic)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.