Description

(1R,3S)-3-Amino-1-(Boc-Amino)Cyclohexane is a high-purity, chiral cyclohexane derivative featuring both a primary amine and a tert-butoxycarbonyl (Boc)-protected amine group. This compound is a critical chiral building block and intermediate in the synthesis of complex pharmaceutical molecules, particularly for active pharmaceutical ingredients (APIs) and drug candidates. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require enantiomerically pure intermediates for asymmetric synthesis and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel APIs, especially in therapeutic areas requiring high stereochemical purity.
• Peptidomimetics & Drug Discovery: Used in the construction of constrained peptide analogs and bioactive molecules due to its rigid cyclohexane scaffold and orthogonal amine protection.
• Asymmetric Synthesis: Serves as a chiral auxiliary or starting material for catalytic asymmetric transformations in fine chemical manufacturing.
• Agrochemical Research: Employed in the synthesis of advanced, enantiopure crop protection agents and herbicides.
• Ligand & Catalyst Development: Useful for creating novel chiral ligands and organocatalysts for industrial catalytic processes.
• Custom Synthesis & Contract Manufacturing: A valuable intermediate for custom synthesis houses serving the pharmaceutical and biotechnology sectors.

Basic Information

Product Name	(1R,3S)-3-Amino-1-(Boc-Amino)Cyclohexane
CAS No.	1259278-17-5
Molecular Formula	C11H22N2O2
Molecular Weight	214.31 g/mol
Synonyms	(1R,3S)-1-((tert-Butoxycarbonyl)amino)-3-aminocyclohexane; (1R,3S)-3-Amino-1-((tert-butoxycarbonyl)amino)cyclohexane; (1R,3S)-1-(Boc-amino)-3-aminocyclohexane; (1R,3S)-1,3-Diaminocyclohexane, 1-N-Boc derivative; (1R,3S)-3-Amino-1-(tert-butoxycarbonylamino)cyclohexane; tert-Butyl ((1R,3S)-3-aminocyclohexyl)carbamate; BOC-ACHA
EINECS	Contact for details

Quality Control

Our (1R,3S)-3-Amino-1-(Boc-Amino)Cyclohexane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with stringent industry standards for pharmaceutical intermediates. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.