Description

tert-Butyl 4-Cyanoazepane-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the azepane class of heterocyclic compounds. This compound is a critical building block in modern medicinal chemistry, valued for its role in constructing complex molecular architectures with potential biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of novel drug candidates, especially those containing the azepane scaffold.
• Medicinal Chemistry Research: Serves as a versatile building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• API Development: Used in the research and process development stages for potential new Active Pharmaceutical Ingredients targeting neurological and psychiatric conditions.
• Chemical Biology Probes: Employed in the synthesis of specialized molecules used to study biological pathways and protein function.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	tert-Butyl 4-Cyanoazepane-1-Carboxylate
CAS No.	1259056-34-2
Molecular Formula	C12H20N2O2
Molecular Weight	224.30 g/mol
Synonyms	1-Boc-4-cyanoazepane; 4-Cyanoazepane-1-carboxylic acid tert-butyl ester; tert-Butyl 4-cyanohexahydro-1H-azepine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-cyanoazepane; Azepane-1-carboxylic acid, 4-cyano-, 1,1-dimethylethyl ester; Boc-4-cyanoazepane; 4-Cyano-1-Boc-azepane
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Cyanoazepane-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our production adheres to cGMP guidelines where applicable, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.