Description

2-Fluoro-4-(Methoxycarbonylmethyl)Benzeneboronic Acid Pinacol Ester, 96% is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in its dual functionality, combining a protected boronic acid group for Suzuki-Miyaura cross-coupling reactions with a versatile methyl ester moiety for further transformations. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly in constructing complex biaryl and heterobiaryl scaffolds. The CAS number for this compound is 1259022-70-2.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), especially those containing fluorinated biaryl structures.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides requiring specific fluorinated aromatic components.
• Material Science: Serves as a monomer or precursor in the creation of advanced organic electronic materials, such as OLEDs and organic semiconductors.
• Ligand Synthesis: Employed in the preparation of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Cross-Coupling Reactions: Primarily designed for robust and efficient Suzuki-Miyaura cross-coupling to form carbon-carbon bonds under mild conditions.

Basic Information

Item	Details
Product Name	2-Fluoro-4-(Methoxycarbonylmethyl)Benzeneboronic Acid Pinacol Ester, 96%
CAS No.	1259022-70-2
Molecular Formula	C15H20BFO4
Molecular Weight	294.13 g/mol
Synonyms	[4-(2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetic acid methyl ester]; Methyl 2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenylacetate; 2-Fluoro-4-(methoxycarbonylmethyl)phenylboronic acid pinacol ester; (4-(Methoxycarbonylmethyl)-2-fluorophenyl)boronic acid pinacol ester; 2-Fluoro-4-(methoxycarbonylmethyl)benzeneboronic acid, pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-(Methoxycarbonylmethyl)Benzeneboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.